CASE REPORT
Introdução: Condrosarcomas intracranianos são tumores malignos extremamente raros de origem cartilaginosa, representando menos de 0,15% de todas as neoplasias intracranianas primárias. Normalmente surgem de sincrondrosas na base do crânio, enquanto locais meníngeos como a falx cerebri são incomuns. Descrição do caso: Uma mulher de 72 anos apresentou dor de cabeça progressiva e fraqueza no membro inferior direito por dois meses. Estudos de neuroimagem revelaram massa parafalcina extra-axial de 5 × 4 cm com calcificações irregulares e aumento mínimo de contraste, inicialmente sugestivo de meningioma. A angiografia computadorizada demonstrou lesão avascular. A paciente foi submetida a ressecção total via craniotomia central esquerda com neuronavegação e neuromonitoramento intraoperatório. A avaliação histopatológica confirmou condrosarcoma grau 2 e as imagens pós-operatórias não mostraram tumor residual. Não foi administrada a radioterapia adjuvante, e recomendado acompanhamento clínico e radiológico rigoroso. Conclusão: Este caso destaca uma apresentação atípica na idade avançada e enfatiza a importância de incluir o condrosarcoma no diagnóstico diferencial de lesões intracranianas calcificadas baseadas em durais.
Introduction: Intracranial chondrosarcomas are exceedingly rare malignant tumors of cartilaginous origin, accounting for less than 0.15% of all primary intracranial neoplasms. They typically arise from skull base synchondroses, whereas meningeal locations such as the falx cerebri are uncommon. Case presentation: A 72-year-old woman presented with progressive headache and right lower extremity weakness for two months. Neuroimaging revealed a 5 × 4 cm extra-axial parafalcine mass with irregular calcifications and minimal contrast enhancement, initially suggestive of meningioma. CT angiography demonstrated an avascular lesion. The patient underwent gross total resection via left central craniotomy with neuronavigation and intraoperative neuromonitoring. Histopathological evaluation confirmed a grade 2 chondrosarcoma. Postoperative imaging showed no residual tumor. Adjuvant radiotherapy was not administered, and close clinical and radiological follow-up was recommended. Conclusion: This case highlights an atypical presentation in advanced age and emphasizes the importance of including chondrosarcoma in the differential diagnosis of calcified, dural-based intracranial lesions.
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1Department of Neurosurgery, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Türkiye.
2Department of Pathology, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Türkiye.
Received Aug 6, 2026
Accepted Aug 13, 2026
